Universal BINATE is created when innate cells from the peripheral blood of prescreened healthy donors are highly co-activated with proprietary GMP grade reagents. The innate cells undergo >1,000 fold expansion without the need for feeder cells.
The production process can be adapted to produce multiple differentiated products:
The BINATE proprietary process has been optimized for large scale, automated, closed system bioreactors.
The process allows the production of thousands of doses of BINATE product from a single donor.
The doses are cryopreserved, release tested and made available off-the-shelf for immediate use.